The CCP5+19 probe is designed to detect the copy number of chromosomes 5 and 19 or to serve as a control to determine the relative copy number of genes located on 5, 19 or other chromosomes.* The probe is derived from specific alpha satellite DNA recognizing chromsomes 5 and 19. 

The CCP5+19 probe is labeled with CytoGreen. CytoGreen is a fluorophore with an excitation peak at 495 nm and emission peak at 518 nm, giving it a green fluorescent signal with the appropriate filters. The probe can also be labeled in different colors; please contact us with your specifications.

The CCP5+19 probe hybridizes to chromosomes 5 and 19 in both metaphase and interphase cells. After hybridizing with normal human peripheral blood lymphocyte samples, four distinct bright fluorescent spots could be observed in the interphase nuclei under a fluorescence microscope. In metaphase cells, bright signals can be observed on the centromere region of chromosomes 5 (5p11.1-q11.1) and 19 (19p111-q11.1).  

* CytoTest shall not be responsible for patent infringement or any other violation that may occur with the use of this product.