The CCP1 probe is designed to detect the copy number of chromosome 1 or to serve as a control to determine the relative number of copies of genes located on chromosome 1 or other chromosomes.* The probe is derived from chromosome 1 specific alpha satellite DNA.

The CCP1 probe is labeled with CytoGreen. CytoGreen is a fluorophore with an excitation peak at 495 nm and emission peak at 518 nm, giving it a green fluorescent signal with the appropriate filters. The probe can also be labeled in different colors; please contact us with your specifications.

The CCP1 probe hybridizes to chromosome 1 in both metaphase and interphase cells. After hybridizing with normal human peripheral blood lymphocyte samples, two distinct bright fluorescent spots could be observed in the interphase nuclei under a fluorescence microscope. In metaphase cells, bright signals can be observed on the centromere region of chromosome 1 (1p11.1-q11.1).  No cross-hybridization to loci on other chromsomes is observed.

* CytoTest shall not be responsible for patent infringement or any other violation that may occur with the use of this product.