Locus Specific Probe for WT1 Gene       

The WT1 FISH Probe is designed to detect the human WT1 gene located on chromosome band 11p13. WT1 is also known as GUD, AWT1, WAGR, WT33, NPHS4, WIT-2 or EWS-WT1.

The WT1 FISH probe is labeled with CytoOrange. CytoOrange is a fluorophore with an excitation peak at 551nm and emission peak at 575nm, giving it an orange fluorescent signal with the appropriate filters.

The WT1 FISH probe hybridizes to chromosome 11 in both metaphase and interphase cells. After hybridizing with normal human peripheral blood lymphocyte samples, two distinct orange fluorescent spots are observed in the interphase nuclei, each spot corresponding to the 11p13 region on the chromosome 11. In metaphase cells, a “doublet” or “split signal” may appear on chromosomal region 11p13. Each signal within the doublet represents one of the two sister chromatids present in the replicated chromosome 11.

* CytoTest shall not be responsible for patent infringement or any other violation that may occur with the use of this product.

Analyte Specific Reagent. Analytical and performance characteristics are not established.