Locus Specific Probe for AHRR Gene       

The AHRR FISH Probe is designed to detect the human AHRR gene located on chromosome band 5p15.33. AHRR is also known as AHH, AHHR or bHLHe77.

The AHRR FISH probe is labeled with CytoGreen. CytoGreen is a fluorophore with an excitation peak at 495nm and emission peak at 518nm, giving it a green fluorescent signal with the appropriate filters.

The AHRR FISH probe hybridizes to chromosome 5 in both metaphase and interphase cells. After hybridizing with normal human peripheral blood lymphocyte samples, two distinct fluorescent spots are observed in the interphase nuclei, each spot corresponding to the 5p15.33 region on the chromosome 5. In metaphase cells, a “doublet” or “split signal” may appear on chromosomal region 5p15.33. Each signal within the doublet represents one of the two sister chromatids present in the replicated chromosome 5.

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Analyte Specific Reagent. Analytical and performance characteristics are not established.