Locus Specific Probe for BCL2L1 Gene    

The BCL2L1 FISH Probe is designed to detect the human BCL2L1 gene located on chromosome band 20q11.21. BCL2L1 is also known as bcl-xS, bcl-xL, PPP1R52,Bcl-X, BCLXS, BCLXL, BCLX, BCL2L or BCL-XL/S.

The BCL2L1 FISH probe is labeled with CytoOrange. CytoOrange is a fluorophore with an excitation peak at 551nm and emission peak at 575nm, giving it an orange fluorescent signal with the appropriate filters.

The BCL2L1 FISH probe hybridizes to chromosome 20 in both metaphase and interphase cells. After hybridizing with normal human peripheral blood lymphocyte samples, two distinct fluorescent spots are observed in the interphase nuclei, each spot corresponding to the 20q11.21 region on the chromosome 20. In metaphase cells, a “doublet” or “split signal” may appear on chromosomal region 20q11.21. Each signal within the doublet represents one of the two sister chromatids present in the replicated chromosome 20.

* CytoTest shall not be responsible for patent infringement or any other violation that may occur with the use of this product.

Analyte Specific Reagent. Analytical and performance characteristics are not established.