The D20S108/CCP8 FISH Probe Kit is designed to detect the human D20S108 STS marker regions located on chromosome band 20q12, along with the number of chromosome 8 copies per cell.* Abnormalities in the D20S108 region are frequently found in myelodysplastic syndrome (MDS), acute myeloid leukemia (AML) and other myeloid disorders. Trisomy 8 is frequently reported in myeloid and lymphoid neoplasias.

The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551 nm and emission peak at 575 nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495 nm and emission peak at 518 nm, giving it an green fluorescent signal with an appropriate filter.