The BRAF-KIAA1549 Fusion/Translocation FISH Probe Kit is designed to detect rearrangements involving the human KIAA1549 locus and the BRAF gene located on chromosome band 7q34. Fusions of KIAA1549 with the BRAF gene – also known as v-raf murine sarcoma viral oncogene homolog B1, NS7, B-raf, BRAF1, RAFB1 or B-RAF1 - have been found in pilocytic astrocytomas and other malignancies.

The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551 nm and emission peak at 575 nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495 nm and emission peak at 518 nm, giving it an green fluorescent signal with an appropriate filter.