The CHL1/CCP3 FISH Probe Kit is designed to detect the human CHL1 gene located on chromosome band 3p26.3, along with the number of chromosome 3 copies per cell. Abnormalities in CHL1 – also known as CALL or L1CAM2 – occur in a variety of cancers including lung, ovarian, esophageal squamous, breast and other malignancies.

The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551 nm and emission peak at 575 nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495 nm and emission peak at 518 nm, giving it an green fluorescent signal with an appropriate filter.