The CDK12/CCP17 FISH Probe Kit is designed to detect the human CDK12 gene located on chromosome band 17q12, along with the number of chromosome 17 copies per cell. Rearrangements and abnormal expression of the CDK12 gene – also known as CRK7, CRKR or CRKRS – have been reported in gastric cancer, ovarian cancer and other malignancies.

The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551nm and emission peak at 575nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495nm and emission peak at 518nm, giving it an green fluorescent signal with an appropriate filter.

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