The DEK/CCP6 FISH Probe Kit is designed to detect the human DEK gene located on chromosome band 6p22.3, along with the number of chromosome 6 copies per cell. Abnormalities in DEK – also known as D6S231E – have been found in acute myeloid leukemia (AML), myelodysplastic syndrome (MDS) and many other hematological malignancies.

The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551nm and emission peak at 575nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495nm and emission peak at 518nm, giving it an green fluorescent signal with an appropriate filter.

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