The CDK14/CCP7 FISH Probe Kit is designed to detect the human CDK14 gene located on chromosome bands 7q21.13, along with the number of chromosome 7 copies per cell. Abnormalities (typically chromosome 7 q-arm deletions) in CDK14 – also known as PFTK1 or PFTAIRE1 – occur in malignant myeloid diseases (ex. CML, AML, etc.) and other malignancies.

The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551nm and emission peak at 575nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495nm and emission peak at 518nm, giving it an green fluorescent signal with an appropriate filter.

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