The CCP13/CCP21 FISH Probe Kit is designed to simultaneously determine the copy number of human chromosomes 13 and 21, and to detect copy number aberrations in these chromosomes, in metaphase and interphase blood and tissue cells. Trisomies of chromosomes 13 and 21 are common prenatal chromosomal aberrations. While the panel can also reveal other copy number defects including mono-, tetra- and polyploidies and other anomalies, a diverse range of specific abnormalities may not be detected by this panel such as localized inversions or balanced intrachromosomal translocations, centromeric polymorphisms, some microdeletions or microduplications, and other defect types.

The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551 nm and emission peak at 575 nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495 nm and emission peak at 518 nm, giving it a green fluorescent signal with an appropriate filter.