The CCND1/CCP11 FISH Probe Kit is designed to detect the human CCND1 gene located on chromosome band 11q13.3, along with the number of chromosome 11 copies per cell.* Abnormal expression of the CCND1 gene – also know as BCL1, D11S287E, PRAD1, or HU21B31 – has been observed in breast carcinoma and a number of other malignancies.

The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551 nm and emission peak at 575 nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495 nm and emission peak at 518 nm, giving it an green fluorescent signal with an appropriate filter.