The BCR-ABL1/ASS1 Tri-color Fusion/Translocation FISH Probe Kit is designed to detect rearrangements involving the human BCR, ABL1 and ASS1 genes located on chromosome bands 22q11.23, 9q34.12 and 9q34.11, respectively.* A reciprocal translocation between the two regions is present in virtually all cases of chronic myelocytic leukemia (CML), but also occurs in a subset of pediatric and adult acute lymphocytic leukemias (ALL), acute myelogenous leukemia (AML) and other malignancies.

The probe is labeled with CytoOrange, CytoGreen and CytoAqua. CytoOrange is a fluorophore with an excitation peak at 551 nm and emission peak at 575 nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495 nm and emission peak at 518 nm, giving it a green fluorescent signal with an appropriate filter; CytoAqua has an excitation peak at 422 nm and emission peak at 471 nm, giving it an aqua fluorescent signal with an appropriate filter.

* CytoTest shall not be responsible for patent infringement or any other violation that may occur with the use of this product.