The CUX1/VIPR2/CCP7 FISH Probe Kit is designed to detect the human CUX1 gene located on chromosome band 7q22.1, and the VIPR2 gene on chromosome band 7q36.3, along with the number of chromosome 7 copies per cell. Expression of the CUX1 gene – also known as CDP, CUX, p75, CASP, CDP1, COY1, Clox, p100, p110, p200, CUTL1, GOLIM6, CDP/Cut, Cux/CDP or Nbla10317 – has been observed elevated in pancreatic, breast and other cancers. Duplications and other anomalies in the region of the VIPR2 gene – also called VPAC2, VPAC2R, VIP-R-2, VPCAP2R, PACAP-R3, DUP7q36.3, PACAP-R-3 or C16DUPq36.3 – are associated with schizophrenia, prenatal malformations and some intestinal malignancies.

The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551 nm and emission peak at 575 nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495 nm and emission peak at 518 nm, giving it an green fluorescent signal with an appropriate filter.