The CCP11 probe is designed to detect the copy number of chromosome 11 or to serve as a control to determine the relative copy number of genes located on chromosome 11 and other chromosomes.* The probe is derived from chromosome 11 specific alpha satellite DNA. 

The CCP11 probe is labeled with CytoGreen. CytoGreen is a fluorophore with an excitation peak at 495 nm and emission peak at 518 nm, giving it a green fluorescent signal with the appropriate filters. The probe can also be labeled in different colors; please contact us with your specifications.

The CCP11 probe hybridizes to chromosome 11 in both metaphase and interphase cells. After hybridizing with normal human peripheral blood lymphocyte samples, two distinct bright fluorescent spots could be observed in the interphase nuclei under a fluorescence microscope. In metaphase cells, bright signals can be observed on the centromere region of chromosome 11 (11p11.1-q11.1). No cross-hybridization to loci on other chromsomes is observed.

* CytoTest shall not be responsible for patent infringement or any other violation that may occur with the use of this product.