The CDKN2A/CCP9 FISH Probe Kit is designed to detect the human CDKN2A gene located on chromosome band 9p21.3, along with the number of chromosome 9 copies per cell.* Abnormalities in CDKN2A – also known as ARF, MLM, P14, P16, P19, CMM2, INK4, MTS1, TP16, CDK4I, CDKN2, INK4A, MTS-1, P14ARF, P19ARF, P16INK4, P16INK4A or P16-INK4A – occur in gliomas and meningiomas as well as numerous other familial and sporadic tumor types.

The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551 nm and emission peak at 575 nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495 nm and emission peak at 518 nm, giving it a green fluorescent signal with an appropriate filter.