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NTRK3 Break Apart FISH Probe Kit   Cat No  CT-PAC244
Acute Lymphocytic Leukemia & Other Malignancies Diagnostic Kit 

The NTRK3 Break Apart FISH Probe Kit is designed to detect rearrangements in the human NTRK3 gene located on chromosome band 15q25.3. In addition to revealing breaks, which can lead to translocation of parts of the gene, inversion, or its fusion to other genes, the probe set can also be used to identify other NTRK3 aberrations such as deletions or amplifications. Rearrangements and abnormal expression of the NTRK3 gene – also known as TRKC, GP145-TrkC or gp145(trkC)  has been observed in medulloblastoma, fibrosacroma, nephroma, some breast cardinoma subtypes and other malignancies. 

The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551 nm and emission peak at 575 nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495 nm and emission peak at 518 nm, giving it an green fluorescent signal with an appropriate filter.

* CytoTest shall not be responsible for patent infringement or any other violation that may occur with the use of this product.



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