The ETV6-NTRK3 Dual Fusion/Translocation FISH Probe Kit is designed to detect rearrangements involving the human ETV6 and NTRK3 genes, located on chromosome bands 12p13.2 and 15q25.3, respectively. ETV6 is also known as TEL, THC5 or TEL/ABL. NTRK3 is also known as TRKC, GP145-TrkC or gp145(trkC). Rearrangements involving portions of these two genes have been observed in acute myeloid leukemia (AML) and other malignancies.

The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551 nm and emission peak at 575 nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495 nm and emission peak at 518 nm, giving it an green fluorescent signal with an appropriate filter.