The AR/CCPX FISH Probe Kit is designed to detect the human androgen receptor (AR) gene located on chromosome band Xq12, along with the number of chromosome X copies per cell. Abnormal expression of the AR gene – also known as TFM, SMAX1, SBMA, NR3C4, KD, HYSP1, HUMARA, DHTR, AR8 or AIS – has been observed in Androgen insensitivity syndrome (AIS), spinal and bulbar muscular dystrophy (Kennedy disease), benign prostatic hyperplasia, prostate adenocarcinoma and other malignancies.

The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551 nm and emission peak at 575 nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495 nm and emission peak at 518 nm, giving it an green fluorescent signal with an appropriate filter.