The ATM/CCP11 FISH Probe Kit is designed to detect the human ATM gene located on chromosome band 11q22.3, along with the number of chromosome 11 copies per cell.* Abnormalities in ATM – also known as AT1, ATA, ATC, ATD, ATE, ATDC, TEL1 or TELO1 – occur in ataxia telangiectasia, and have also been observed in chronic lymphocytic leukemia (CLL) and other malignancies.
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The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551 nm and emission peak at 575 nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495 nm and emission peak at 518 nm, giving it an green fluorescent signal with an appropriate filter.
* CytoTest shall not be responsible for patent infringement or any other violation that may occur with the use of this product. |