The BRAF/CCP7 FISH Probe Kit is designed to detect the human BRAF gene located on chromosome band 7q34, along with the number of chromosome 7 copies per cell. Abnormalities in BRAF – also known as v-raf murine sarcoma viral oncogene homolog B1, BRAF1 or RAFB1 – have been found in solid tumors like melanoma, colorectal cancer, ovarian cancer, papillary thyroid cancer and other malignancies.

The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551nm and emission peak at 575nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495nm and emission peak at 518nm, giving it a green fluorescent signal with an appropriate filter.

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