The BCL2L1/CCP20 FISH Probe Kit is designed to detect the human BCL2L1 gene located on chromosome band 20q11.21, along with the number of chromosome 20 copies per cell. Abnormal expression of the BCL2L1 gene – also known as bcl-xS, bcl-xL, PPP1R52, Bcl-X, BCLXS, BCLXL, BCLX, BCL2L or BCL-XL/S – has been observed in acute lymphoblastic leukemia (ALL), chronic lymphocytic leukemia (CLL), follicular lymphomas, non-Hodgkin's lymphoma and various types of solid tumors such as breast, lung, bladder, cervix, prostate, glioblastoma and others.

The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551 nm and emission peak at 575 nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495 nm and emission peak at 518 nm, giving it an green fluorescent signal with an appropriate filter.