The ASPSCR1-TFE3 Fusion/Translocation FISH Probe Kit is designed to detect rearrangements involving the human ASPSCR1 and TFE3 genes located on chromosome bands 17q25.3 and Xp11.23, respectively. Fusion of ASPSCR1 – also known as TUG, ASPL, ASPS, RCC17, UBXD9, UBXN9 or ASPCR1 – with the TFE3 gene – also known as TFEA,RCCP2, RCCX1 or bHLHe33 – on the X chromosome has been observed in alveolar soft part sarcoma and a subset of renal cell carcinomas. 

The probe is labeled with CytoOrange and CytoGreen. CytoOrange is a fluorophore with an excitation peak at 551 nm and emission peak at 575 nm, giving it an orange fluorescent signal with an appropriate filter; CytoGreen has an excitation peak at 495 nm and emission peak at 518 nm, giving it an green fluorescent signal with an appropriate filter.

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